Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Jul 2021
Observational StudyHigh-flow nasal oxygen therapy in the treatment of acute respiratory failure in severe COVID-19 pneumonia: a prospective observational study.
A significant proportion of patients with COVID‑19 present with a rapidly progressing severe acute respiratory failure. ⋯ The results of our study suggest that nearly half of patients treated with HFNO due to severe COVID‑19 pneumonia will require mechanical ventilation. The ROX index is a useful tool for predicting HFNO failure in this population.
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Pol. Arch. Med. Wewn. · Jul 2021
Granulomatosis with Polyangiitis and Nasal Involvement - What Radiological Markers Point the Disease.
Granulomatosis with polyangiitis (GPA) is an autoimmune disease leading to necrotizing lesions in the affected tissues. Computed tomography (CT) of paranasal sinuses reveals multiple lesions in patients with GPA, for example, sinus opacification, bone / cartilage destruction, and neoosteogenesis. ⋯ Nasal strands, a parameter reflecting pathologic mucus and atrophic lesions (tissue loss), should have a place in CT evaluation of the nasal cavities in patients suspected of or diagnosed with GPA.
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Pol. Arch. Med. Wewn. · Jul 2021
Polyunsaturated fatty acids in cardiovascular diseases: uncertainty prevails.
In the late 1970s, a lower incidence of myocardial infarction and favorable hemostatic alterations were reported in Greenland Inuits. This observation prompted investigators worldwide to continue research on the role of a specific diet in this population and sparked an ongoing discussion about the potential use of polyunsaturated fatty acids (PUFAs) in the primary prevention of cardiovascular disease (VITAL), and the secondary prevention of primarily coronary artery disease (JELIS, REDUCE‑IT, OMEMI). ⋯ The questions remain whether eicosapentaenoic acid is the only PUFA offering cardiovascular benefits, what is the importance of PUFA dosing, and, finally, who should receive n-3 PUFA treatment. This article discusses the latest insights into n-3 PUFA use in cardiovascular disease prevention.
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Pol. Arch. Med. Wewn. · Jul 2021
Multicenter StudyExtremely high mortality in COVID-19 hemodialyzed patients in before anty-SARS-CoV-2 vaccination era. The first large database from Poland.
Preliminary reports suggested high incidence and mortality rates of SARS‑ CoV 2 infection in patients receiving kidney replacement therapy. ⋯ The results of this study show the extremely high mortality rate of COVID‑ 19 in hemodialysis patients during the first and second waves of the epidemic in Pomerania Province, before the vaccination era.
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Pol. Arch. Med. Wewn. · Jun 2021
Meta AnalysisAssociation between cardiovascular diseases and depressive symptoms in adults. A pooled analysis of population-based surveys WOBASZ, NATPOL2011 and WOBASZ II.
INTRODUCTION Psychosocial risk factors play an important role in the origins of cardiovascular risk. OBJECTIVES The aim of the study was to evaluate the prevalence of depressive symptoms (DSs) in relation to some sociodemographic characteristics and selected cardiovascular diseases (CVDs) and to assess the relationship between self‑reported CVDs and the severity of DSs. PATIENTS AND METHODS Three cross‑sectional population‑based surveys: WOBASZ (2003-2005), NATPOL 2011 (2011), and WOBASZ II (2013-2014) covered a total sample of 20 514 participants (9614 men and 10 900 women), aged 20 to 74 years, who all completed the Beck Depression Inventory. ⋯ Individuals with DSs, both men and women, even those with borderline depression, had from 1.5- to more than 2‑fold higher odds of either coronary artery disease or arrhythmia, and 2- to almost 4‑fold higher chance of previous stroke in their medical history. CONCLUSIONS This study showed that DSs were a frequently observed condition in the general Polish population including patients with CVDs. We also demonstrated that there is a relationship between self‑reported CVDs and severity of DSs regardless of age, marital status, education, and concomitant disorders.