Sheng li xue bao : [Acta physiologica Sinica]
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Experiments were performed on male SD rats anaesthetized with urethane (700 mg/kg) and chloralose (35 mg/kg). The results showed that mean arterial pressure (MBP) increased signifigantly and heart rate (HR) had no signifigant change by bilateral microinjection AVP(10 pmol/0.1 microliter/site) into the rostral ventrolateral medulla (rVLM), while both MBP and HR were not changed by application of an AVP-V1 receptor antagnoist. ⋯ The above results suggest that AVP in the rVLM can elevate MBP and midbrain defence area stimulation can cause pressor response. Both these effects are related to activation of AVP-V1 receptors in the rVLM.