Recenti progressi in medicina
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Oral tissue damage and mucositis pain can be a significant problem for patients. The frequency and severity of these problems can vary significantly from patient to patient. Oral complications primarily are associated with discomfort and interference with oral function. ⋯ The body uses pain to tell the brain that something is wrong. Never ignore pain. Any type of pain symptom needs prompt professional medical advice for diagnosis of the underlying cause of the pain.
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Vertebral fractures are the most common consequences of severe osteoporosis. The chronic pain from collapse of osteoporotic vertebrae affects quality of life and autonomy of patients. The management of pain with oral or transdermal opiates can cause severe side-effects. Continuous intrathecal administration of morphine with an implantable pump represents a good alternative therapy and has advantages in pain relief and quality of life. ⋯ Our results show that intrathecal administration of morphine efficiently relieves the symptoms of pain and improve the quality of life. Continuous intrathecal administration of morphine represents a good alternative therapy and has advantages in those patients who suffer from severe side-effects with systemic administration.