Annals of the American Thoracic Society
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Meta Analysis
Maximal Static Respiratory and Sniff Pressures in Healthy Children. A Systematic Review and Meta-Analysis.
Respiratory muscle strength in children can be assessed by maximal inspiratory pressures (MIP), maximal expiratory pressures (MEP), and sniff nasal inspiratory pressures (SNIP). However, previous studies involved small cohorts of healthy children and reported wide reference ranges. ⋯ We summarized the available reference ranges for MIP, MEP, and SNIP tests based on existing literature, especially for three age groups, and developed prediction equations that can be used in pulmonary function laboratories to aid clinicians. Existing literature on SNIP tests is limited, and future studies are encouraged to explore their use in children. Systematic review registered with the International Prospective Register of Systematic Reviews (PROSPERO; CRD42017072004).
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Randomized Controlled Trial
Physical Function Trajectories in Survivors of Acute Respiratory Failure.
Survivorship from critical illness has improved; however, factors mediating the functional recovery of persons experiencing a critical illness remain incompletely understood. ⋯ We identified distinct trajectories of physical function recovery after critical illness. Age, sex, continuous sedation time, and ICU length of stay impact the trajectory of functional recovery after critical illness. Further examination of these groups may assist in clinical trial design to tailor interventions to specific subgroups.