Zhonghua zhong liu za zhi [Chinese journal of oncology]
-
Zhonghua Zhong Liu Za Zhi · Jul 2007
[Whole brain irradiation for non-small-cell lung cancer with brain metastasis].
To investigate the time of whole brain irradiation and the prognostic factors for non-small lung cancer patients with brain metastasis. ⋯ The extracranial metastasis in non-small cell lung cancer patients with brain metastasis is an independent prognostic factors. Early whole brain irradiation may improve the survival for those with brain metastasis symptoms.
-
Zhonghua Zhong Liu Za Zhi · Jul 2007
[CDK1 expression and effects of CDK1 silencing on the malignant phenotype of glioma cells].
Our previous cDNA array data have shown that expression level of CDK1 increased along with the malignant progression of ganglioglioma, and decreased with the differentiation process of neural stem cells. The purpose of this study was to investigate the CDK1 expression levels in gliomas and the effects of CDK1 knockdown on phenotype of glioma cells. ⋯ Overexpression of CDK1 may promote oncogenesis and progression of human gliomas. Downregulation of CDK1 expression can inhibit the proliferation activities of human malignant gliomas.