Zhonghua zhong liu za zhi [Chinese journal of oncology]
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Zhonghua Zhong Liu Za Zhi · Aug 2007
[Influence of number of removed lymph nodes on the TNM staging and survival in advanced esophageal carcinoma].
To evaluate the impact of total number of removed regional lymph nodes (LN) during esophagectomy on TNM staging and long-term survival. ⋯ A large series of retrospective study on advanced squamous cell carcinoma of the thoracic esophagus demonstrates that the number of metastatic LN is an important prognostic factor, therefore, it should be considered when refining UICC-TNM classification for esophageal cancer. If the total number of LN removed during each esophagectomy is less than 6, the occult positive regional LN might be missed, resulting in an inaccurate N classification and incorrect staging. Removal of > or = LN for each esophageal cancer patient during esophagectomy recommended by UICC is rational and should be complied with.
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Zhonghua Zhong Liu Za Zhi · Jul 2007
[Whole brain irradiation for non-small-cell lung cancer with brain metastasis].
To investigate the time of whole brain irradiation and the prognostic factors for non-small lung cancer patients with brain metastasis. ⋯ The extracranial metastasis in non-small cell lung cancer patients with brain metastasis is an independent prognostic factors. Early whole brain irradiation may improve the survival for those with brain metastasis symptoms.
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Zhonghua Zhong Liu Za Zhi · Jul 2007
[CDK1 expression and effects of CDK1 silencing on the malignant phenotype of glioma cells].
Our previous cDNA array data have shown that expression level of CDK1 increased along with the malignant progression of ganglioglioma, and decreased with the differentiation process of neural stem cells. The purpose of this study was to investigate the CDK1 expression levels in gliomas and the effects of CDK1 knockdown on phenotype of glioma cells. ⋯ Overexpression of CDK1 may promote oncogenesis and progression of human gliomas. Downregulation of CDK1 expression can inhibit the proliferation activities of human malignant gliomas.
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Zhonghua Zhong Liu Za Zhi · Apr 2007
[A case-control study on genetic polymorphism of CYP17 MspA(1)I and its association with endometrial cancer risk].
To assess whether the polymorphisms of CYP17 MspA(1)I are associated with the susceptibility of endometrial cancer. ⋯ No significant relationship was found between CYP17 MspA(1)I genotypes and endometrial cancer risk.
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Zhonghua Zhong Liu Za Zhi · Mar 2007
[Evaluation of 2D and 3D MRI imaging in the diagnosis of pancreatic carcinoma].
To evaluate various kinds of sequences and modified dynamic contrast-enhanced MRI methods in the diagnosis of pancreatic carcinoma. ⋯ As"one-stop-shop" MRI examination, modified MRI sequences consisting of dynamic coronal and axial contrast-enhanced scanning is feasible and helpful in diagnosing, staging and assessing the resectability for pancreatic carcinoma.