Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
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Pol. Merkur. Lekarski · Feb 2008
Review[The role of anaerobic bacteria in peritonsillar abscesses].
Peritonsillar abscess (quinsy) is a complication of acute bacterial tonsillitis. Its treatment remains controversial. Needle drainage of the abscess may provide an alternative to incision or tonsillectomy. ⋯ It is, however, necessary to consider infection with anaerobes. Therefore, penicillin and metronidazole are recommended as the antibiotic regimen of choice in the treatment of peritonsillar abscesses. If this treatment is ineffective, broad-spectrum antibiotics (clindamycin) should be administered.
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Delirium presents as a diagnosis joining closely other medical disciplines. Because of its serious prognosis, precise causal diagnostic is required. Selective therapy, to avoid serious prognosis, is possible when delirium is early diagnosed and ethiology is established. The present work is to remind risk factors of delirium, to explain mechanisms responsible for development of delirium based on various etiology, show biomarkers helpful in making diagnosis, and pay special attention to prodromal symptoms and clinical forms.
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Pol. Merkur. Lekarski · Feb 2008
Comparative Study[The assessment of nitric oxide metabolites in gastric juice in Helicobacter pylori infected subjects in compliance with grade of inflammatory lesions in gastric mucosa].
The infection of H. pylori causes inflammatory lesions in gastric mucosa--until atrophic gastritis, intestinal metaplasia, dysplasia (precancerous states) and finally to gastric cancer or lymphoma. The mechanism of mentioned disturbances is complicated, no doubt that nitric oxide plays here very important role. It is proved, that H. pylori causes essential oxygen metabolism disturbances by activation of inflammatory infiltration's cells to oxide reactive forms as nitric oxide formation. Nitric oxide as oxide radical could react with other free radicals and contribute to oxidative lesions of gastric mucosa and alterations of its structure. The aim of the study was try to answer the question: 1. Is this the relationship between NO metabolites concentrations in gastric juice and morphological state of gastric mucosa? 2. Does H. pylori eradication influence on NO metabolites concentrations in gastric juice? 3. Does H. pylori eradication influence on grade of inflammatory lesions in gastric mucosa? ⋯ 1. The increase of NO metabolites concentration demonstrates positive correlation with grade of inflammatory lesions in gastric mucosa. 2. The effective antibacterial therapy causes the decrease of NO metabolites concentration in gastric juice, especially in patients with chronic active gastritis. 3. Eradication influence on decrease of grade of lesions' progression in gastric mucosa just in 12 months after effective antibacterial therapy.