Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
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Pol. Merkur. Lekarski · May 2011
Review[Antimicrobial therapy of severe infections in critically ill patients].
Antimicrobial therapy of severe infections in critically ill patients becomes an important clinical problem. One of the reason is increasing resistance of pathogens to antibiotics. In this paper the current problems of the treatment of severe infections in Intensive Care Units' patients were discussed as well as benefits of modern antimicrobial agents were presented.
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Pol. Merkur. Lekarski · May 2011
Review[Antibiotic therapy in community acquired pneumonia in children].
Pneumonia is still the main cause of initiation antibiotic therapy in children, despite the fact that according to the newest epidemiological data, its incidence seems to be lower. In this paper current data concerning etiology, diagnostics and guidelines are discussed. The empirical antibiotic therapy of childhood pneumonia in different age groups is described. Author showed future trends in research necessary to solve controversies in present guidelines.
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Drug-resistant tuberculosis, and particularly multidrug-resistant tuberculosis (MDR-TB) and extensive drug resistant TB (XDR-TB) as an increasing health problem and a serious challenge to TB control programs. MDR-Tb and XDR-TB are highly lethal in people living with HIV, with case of fatality rates of over 90%. At the same time, there are not many drugs effective in TB chemotherapy. ⋯ Drug resistance in tuberculosis patients have been monitored in Poland for a long time. In period of recent 30 years the mean frequency of resistant was on the similar level with very low rate of RMP mono-resistance to M. tuberculosis. Both type of resistance MDR and XDR have been found in Polish tuberculosis patients.
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Pol. Merkur. Lekarski · May 2011
Review[Effectiveness and tolerance of antibiotics in pediatrics patients].
Antibiotics represent the most widely prescribed therapeutic agents. Preschool children being most exposed to antibiotic drugs, especially in the community setting. ⋯ Early antibiotic exposure, especially to broad-spectrum antibiotics, may suppress the developing immune system and produce a reduced anti-allergic response. Early antibiotic use in children is associated with an increased risk for asthma.