European review for medical and pharmacological sciences
-
Eur Rev Med Pharmacol Sci · Jul 2014
Understanding pharmacokinetics: are YouTube videos a useful learning resource?
To investigate whether YouTube videos on pharmacokinetics can be a useful learning resource for medical students. ⋯ YouTube videos on pharmacokinetics and drug elimination showed a range of variability in regard to the contents of their educational usefulness. Medical educators should be aware of the potential influence of YouTube videos may have on student's understanding of pharmacokinetics and drug elimination. Users who rely on the comments made by viewers or the approval expressed in terms of the number of like given by viewers should become aware that these indicators are not accurate and do not correlate with the scores given to videos.
-
Eur Rev Med Pharmacol Sci · Jul 2014
Dexmedetomidine protects against ischemia/reperfusion injury in rat kidney.
Ischemia/reperfusion (I/R) injury in the kidney during perioperative period remains the leading cause of acute renal failure. The purpose of this experimental study was to determine the role of dexmedetomidine (Dex) on renal I/R injury in rats. ⋯ Our data suggest that anti-apoptosis effect contributes to the renoprotection of dexmedetomidine, via inhibiting JAK2/STAT3 signaling pathway partially.
-
Eur Rev Med Pharmacol Sci · Jul 2014
A mechanism study on propofol's action on middle latency auditory evoked potential by neurons in ventral partition of medial geniculate body in rats.
To investigate the effect of propofol on the middle latency auditory evoked potentials (MLAEP) by neurons in the ventral partition of medial geniculate body (MGBv) in rats and study their mechanism. ⋯ Propofol in 56 µmol/L, 168 µmol/L and 560 µmol/L can inhibit MLAEP in MGBv of rats in a dose-dependent manner and these changes may be caused by blocking the ion channel of persistent sodium currents and high voltaged activated calcium currents.
-
Eur Rev Med Pharmacol Sci · Jul 2014
ReviewBrain hypothermia therapy for status epilepticus in childhood.
At the Dokkyo Medical University Hospital, we introduced a brain hypothermia therapy protocol for treating childhood status epilepticus and acute encephalitis/encephalopathy in 2004. ⋯ This paper reviews the brain hypothermia therapy protocol.
-
Eur Rev Med Pharmacol Sci · Jul 2014
Does the STOP-Bang, an obstructive sleep apnea screening tool, predict difficult intubation?
A close relationship between obstructive sleep apnea (OSA) and difficult intubation has been suggested. We hypothesized that the STOP-Bang questionnaire, a screening tool for obstructive sleep apnea (OSA), can predict difficult intubation. ⋯ A STOP-Bang score of ≥ 3 was a predictor for difficult intubation.