European review for medical and pharmacological sciences
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Eur Rev Med Pharmacol Sci · May 2018
The correlation of plasma microRNA-200 family expressions with risk and disease severity of lupus nephritis.
To investigate whether plasma microRNA-200 family expressions could serve as diagnostic biomarkers in patients with lupus nephritis (LN), and their association with disease severity. ⋯ Circulating miR-200b-5p, miR-141-5p, and miR-200c-5p expressions could be served as novel and convincing diagnostic biomarkers for LN.
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Eur Rev Med Pharmacol Sci · May 2018
Tirofiban combined with rt-PA intraarterial thrombolysis improves the recanalization rate of acute middle cerebral artery occlusion in rabbits.
To investigate the curative effect of tirofiban combined with recombinant tissue-plasminogen activator (rt-PA) selective intra-arterial thrombolysis on acute middle cerebral artery occlusion (MCAO). ⋯ Early application of tirofiban combined with rt-PA in intra-arterial thrombolysis for ultra-early cerebral ischemia can improve the recanalization rate of cerebral artery. The time of cerebral ischemia and hypoxia is short, and the neuronal ischemia-reperfusion injury is mild, whose thrombolysis effect is better than the single application of tirofiban or rt-PA.