Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Mar 1999
Randomized Controlled Trial Clinical Trial[Fentanyl reduces the MAC of sevoflurane].
To determine the interaction between fentanyl and sevoflurane following a bolus injection of fentanyl after induction iwth sevoflurane inhalation only. ⋯ The MAC of sevoflurane is significantly reduced 20 minutes after a single dose of 3 ng/kg of fentanyl and that increasing the fentanyl dose to 6 ng/kg produces a little further decrease in MAC of sevoflurane.