Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Feb 2007
Comparative Study[3-dimension computed tomography angiography and digital subtraction angiography in diagnosis of intracranial aneurysm: a comparative study].
To compare the appliance values off 3-dimension computed tomography (CTA) and digital subtraction angiography (DSA) in diagnosis of intracranial aneurysm (ICA). ⋯ 3D-CTA is the first choice examination technique for patients with subarachnoid hemorrhage. The information obtained by 2D-DSA, 3D-DSA, and 3D-CTA should be considered comprehensively.
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Zhonghua yi xue za zhi · Feb 2007
[Expression of connective tissue growth factor in renal interstitial fibrosis after ureteral obstruction and effects of rapamycin thereupon: experiment with rats].
Is a common feature of progressive renal diseases regardless of the initiating insult To clarify the role of connective tissue growth factor (CTGF) in after (UUO) in renal interstitial fibrosis and effects of rapamycin (RAP) thereupon. ⋯ The expression of CTGF mRNA and that of CTGF protein increase after UUO. Rapamycin play a protective role in the kidney by downregulating the CTGF expression and alleviating the renal interstitial fibrosis following UUO.
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Zhonghua yi xue za zhi · Feb 2007
Randomized Controlled Trial Multicenter Study[Clinical trial with a new immunomodulatory strategy: treatment of severe sepsis with Ulinastatin and Maipuxin].
To evaluate the efficacy of treatment of severe sepsis by combining anti-inflammatory and immune-enhancing agents. ⋯ Treatment by the combining anti-inflammatory and immune enhancing agents can significantly improve the outcome of severe sepsis. The efficacy of this therapy seems to be dose dependent on.
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To investigate the expression profile of integrin genes in heart of septic rat and relevant mechanisms responsible for sepsis-induced heart injury. ⋯ Maladjustment in expression of integrin genes is present in the septic rat heart. Up-regulation of integrin alphaV and beta2 genes may accelerate the heart injury mediated by inflammatory mediators, and the relatively insufficient expression of integrin beta1 gene may contribute to cardiac dysfunction.