Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Jul 2009
Controlled Clinical Trial[Sequential study of radiotherapy and hormonal therapy in breast cancer patients undergoing mastectomy or conservative surgery].
To investigate the optimal sequence of adjuvant radiotherapy and hormonal therapy in patients with breast cancer. ⋯ The sequential or concurrent sequence of adjuvant radiotherapy and hormonal therapy does not affect the local control and survival prognosis significantly, especially with TAM. However, TAM administered concurrently with radiotherapy slightly increases the occurrence rate of lung and skin fibrosis. Concurrent administration of AI and sequential TAM with radiotherapy is preferred in clinical practice. Further prospective randomized trials will be needed to validate these results.
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Zhonghua yi xue za zhi · Jul 2009
[Selection of surgical methods for lumbar disc herniation with degenerative endplates changes].
To analyze the selection of surgical methods for lumbar disc herniation with low back and leg pain and degenerative lumbar Modic endplate changes and their different postoperative therapeutic effects. ⋯ For lumbar disc herniation with degenerative Modic endplate changes, who suffered more from low back pain than lower extremity radicular pain, discectomy alone and decompression with interbody fusion could both improve the degree of lower extremity radicular pain, but discectomy alone is less likely to improve the degree of low back pain and function score than the latter. So the maneuver of lumbar decompression with fusion is a better choice.
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Zhonghua yi xue za zhi · Jul 2009
Randomized Controlled Trial[Clinical assessment of ProSeal laryngeal mask airway during total hip replacement operation].
To assess the value of ProSeal-LMA (laryngeal mask airway) during hip replacement operation. ⋯ ProSeal-LMA can be applied in hip replacement operation because of its simple handling, lesser effects upon respiration and circulation and fewer post-operative complications.
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Zhonghua yi xue za zhi · Jul 2009
[Efficacy of continuous positive airway pressure therapy upon resistant hypertension in patients with obstructive sleep apnea hypopnea syndrome].
To investigate the efficacy and possible mechanism of continuous positive airway pressure (CPAP) therapy upon blood pressure in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and resistant hypertension (RH). ⋯ CPAP therapy could significantly improve RH and plasma ALD concentration. Elevated plasma ALD concentration is possibly involved in the pathogenesis of RH in OSAHS patients.
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Zhonghua yi xue za zhi · Jul 2009
Comparative Study[Comparative study on clinical and pathological changes of liver fibrosis with diffusion-weighted imaging].
To evaluate the clinical practical value of apparent diffusion coefficient (ADC) measurements based on diffusion-weighted MR imaging (DWI) for quantification of liver fibrosis and inflammation for hepatitis viral infection. ⋯ The DWI measurement of hepatic ADC can be used to quantify liver fibrosis and inflammation. It will be a new approach for early diagnosis and therapeutic follow-up of hepatic fibrosis.