Zhonghua yi xue za zhi
-
Zhonghua yi xue za zhi · Aug 2009
[Change in plasma microparticle procoagulant activity after traumatic brain injury].
To observe the serial changes of plasma microparticle procoagulant activity in patients with traumatic brain injury (TBI) and evaluate its correlations with outcome and pathophysiology of TBI. ⋯ Increased activity of plasma microparticle procoagulant is found after traumatic brain injury. It may contribute to inflammatory reaction and coagulation cascade and is associated with a poor clinical outcome.
-
Zhonghua yi xue za zhi · Aug 2009
[Role of central neuronal nicotinic receptor in the inhibitory effect of isoflurane on synaptic long-term potentiation in hippocampal slices of rats].
To determine effect of central neuronal nicotinic receptor on synaptic long-term potentiation (LTP) in the CA1 area of rats hippocampal slices. ⋯ The inhibition of LTP induction may contribute to isoflurane-induced deficits in memory, and the underlying mechanism is involved in the inhibition of nicotinic acetylcholine receptor activation in hippocampus of rats.
-
Zhonghua yi xue za zhi · Aug 2009
[Expression of metabotropic glutamate receptor 5 in spinal cord of morphine tolerant rats].
To investigate the expression of metabotropic glutamate receptor 5 (mGluRS) in spinal cord of morphine tolerant rats and understand the influence of mGluR5 antagonist MPEP upon the expression of mGluRS. ⋯ The mGluR5 antagonist MPEP can prevent the development of morphine tolerance. The expression of mGluR5 protein increases in the spinal cord of morphine tolerant rats. MPEP plays its role in morphine tolerance by partly inhibiting the expression of mGluRS.
-
Zhonghua yi xue za zhi · Aug 2009
Randomized Controlled Trial[Natural history and prognosis of discogenic low back pain].
To understand the natural history and prognosis of patients with discogenic low back pain so as to offer a better guide on its clinical treatment. ⋯ The disease course of discogenic low back pain is chronic and persistent so that its symptoms show no improvement over time.
-
Zhonghua yi xue za zhi · Aug 2009
Comparative Study[Comparison of adenosine versus iloprost by acute vasodilator test in patients of pulmonary arterial hypertension complicated with connective tissue diseases].
To compare the acute hemodynamic effects of adenosine versus iloprost in patients of pulmonary arterial hypertension (PAH) complicated with connective tissue diseases. ⋯ During acute vasodilator testing, inhaled iloprost was more potent than infused adenosine as a pulmonary vasodilator in PAH complicated with connective tissue diseases.