Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Feb 2009
[Influence of neuromuscular blockade on motor evoked potential of forearm muscles].
To investigate the influence of different degrees of neuromuscular blockade on motor evoked potential (MEP) of forearm muscles under the same condition of anesthesia depth and analgesia. ⋯ Neuromuscular blocking drugs significantly depress the MEP in a dose-dependent manner. Intra-operatively it may be preferable to maintain the value of TOF not less than 2 during the critical periods of MEP monitoring.
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Zhonghua yi xue za zhi · Feb 2009
Randomized Controlled Trial[Effects of patient-controlled analgesia with small dose ketamine combined with morphine and the influence thereof on plasma beta-endorphin level in patients after radical operation for esophageal carcinoma].
To evaluate the effects of patient-controlled analgesia (PCA) with small dose ketamine combined with morphine on analgesia and influence thereof on the plasma beta-endorphin (EP) level in the patients after radical operation for esophageal carcinoma. ⋯ The combination of small dose of ketamine with morphine provides optimal analgesia with low side-effect rate and little effect on the plasma beta-EP level.
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Zhonghua yi xue za zhi · Feb 2009
[Bone morphogenetic protein type II receptor gene promoter mutation-142G > A in a patient with familial pulmonary arterial hypertension].
To investigate the relation between bone morphogenetic protein type II receptor (BMPR2) gene promoter mutation and pulmonary arterial hypertension (PAH). ⋯ BMPR2 promoter mutation -142G > A may be associated with FPAH.
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Zhonghua yi xue za zhi · Feb 2009
Controlled Clinical Trial[Relationship of serum Chemerin to obesity and type 2 diabetes mellitus].
To detect the serum Chemerin levels in patients with obesity and newly diagnosed type 2 diabetes mellitus (T2DM) and explore the relationship of serum Chemerin to body fat parameters, glucose and lipid metabolism, and insulin resistance index (IR). ⋯ Serum Chemerin levels are much higher in females and obese subjects are much higher than in men and subjects with normal weight. Serum Chemerin is correlated with insulin level, body fat disposition and lipid metabolism which suggesting that it may play a role in the pathophysiology of obesity and metabolic syndrome.
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Zhonghua yi xue za zhi · Jan 2009
Randomized Controlled Trial[Effects of ulinastatin on coagulation and platelet function in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass].
To investigate the effects of ulinastatin (U) on coagulation, platelet function, and postoperative bleeding in patients undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB). ⋯ Ulinastatin shortens the APTT and ACT after heparinization, increases the dose of heparin during CPB, has no effect on the expression of GP IIb-IIIa and CD62p, and does not reduce postoperative blood loss.