Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Dec 2019
Meta Analysis[Systematic evaluation of neuromuscular blocking agents on prognosis of patients with moderate to severe acute respiratory distress syndrome].
Objective: To evaluate the prognostic impact of neuromuscular blocking agents (NMBA) on patients with acute respiratory distress syndrome (ARDS). Method: Online search of MEDLINE, Embase, Web of Science, CNKI, CBM and other Chinese databases for randomized controlled trials (RCTs) of NMBA in patients with ARDS from January 1994 to June 2019 was done, and literature was selected according to inclusion and exclusion criteria. The patients were divided into NMBA group and non-NMBA group according to whether NMBA was adopted or not. ⋯ Results: A total of 6 RCTs were included, and 1 502 patients were enrolled, including 761 in the NMBA group and 741 in the no-NMBA group. The 90-day mortality in the NMBA group and no-NMBA group were 38.8% and 42.6%, OR=0.87 (95%CI: 0.70-1.07, P=0.190); the 28-day mortality rates were 32.5% and 36.5%, OR=0.71 (95%CI: 0.45-1.11, P=0.130); ICU mortality rates were 31.8% and 43.8%, OR=0.60 (95%CI: 0.41-0.88, P=0.009). Conclusion: NMBA can reduce the ICU mortality of moderate to severe ARDS patients, but not reduce 28-day and 90-day mortality.
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Zhonghua yi xue za zhi · May 2016
Meta Analysis[A meta-analysis of perioperative hyperoxia for the surgical site infections in patients with general surgery].
To systemically analyze the effect of perioperative hyperoxia for the surgical site infections in patients with general surgery. ⋯ Perioperative hyperoxia does not reduce surgical site infections in patients with general surgery. However, the results of two subgroup analyses (colorectal surgery and intraoperative plus postoperative 6 h oxygen inhalation trials) show a significantly benefit for perioperative hyperoxia in decreasing surgical site infections.
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Zhonghua yi xue za zhi · May 2015
Meta Analysis[A meta-analysis of preoperative versus intraoperative endoscopic sphincterotomy in patients with gallbladder and suspected common bile duct stones].
To compare the safety and efficiency of preoperative endoscopic sphincterotomy (POES) versus intraoperative endoscopic sphincterotomy (IOES) in patients with gallbladder and common bile duct stones. ⋯ With regards to stone clearance and overall complication rate, POES is comparable to IOES in patients with gallbladder and common bile duct stones. However, IOES has a lowered incidence of ERCP-related pancreatitis and a shorter hospital stay.
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Zhonghua yi xue za zhi · Jul 2014
Meta Analysis[High-frequency oscillatory ventilation in patients with acute respiratory distress syndrome: a meta-analysis].
To evaluate the effects of high-frequency oscillatory ventilation (HFOV) on mortality in patients with acute respiratory distress syndrome (ARDS). ⋯ Compared with CMV, HFOV dose not improve prognosis in adult patients with ARDS. Thus more high-quality RCTs with larger samples are warranted.
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Zhonghua yi xue za zhi · Sep 2013
Meta Analysis[Effects of gastric versus small bowel feeding on hospital acquired pneumonia in critically ill patients: a meta-analysis].
To explore whether or not small bowel feeding can reduce the incidence of hospital acquired pneumonia (HAP). ⋯ Compared with gastric feeding, small bowel feeding can reduce the incidence of HAP, especially VAP, but can not reduce the mortality.