Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Aug 2005
[The characteristics during exercise test in long QT syndrome patients and the effects of left cardiac sympathetic denervation].
To explore the mechanism of the left cardiac sympathetic denervation (LCSD) surgery to reduce the incidence of cardiac events for long QT syndrome (LQTS) patients. ⋯ The slope between QT and RR both the pre-exercise and post-exercise slopes, interval becomes less steep after LCSD, which suggests that exaggerated delay in repolarization with decreasing heart rate for LQTS patients is improved by LCSD. This may be one of the mechanisms of LCSD efficacy for treating LQTS patients. Exercise test is one of tools to evaluate the effect of LCSD on LQTS patients.
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To evaluate the dosing regimens of levofloxacin. ⋯ The proposed dosing regimens of levofloxacin based on PK/PD concepts are expected to provide good efficacy in clinical practice.