Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Sep 2003
[Prognostic value of MRI and 1H MRS in patients with temporal lobe epilepsy].
To evaluate the prognostic value of hippocampal MRI scan, MRI volumetry and 1H MRS in patients with temporal lobe epilepsy (TLE). ⋯ Hippocampal MRI scan, MRI volumetry and 1H MRS may be used as prognostic tools in TLE patients before surgery. The combination of several noninvasive methods before surgery can help choose suitable patients for surgery, and, as a result, improve surgical outcome.
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Zhonghua yi xue za zhi · Aug 2003
Randomized Controlled Trial Clinical Trial[Myocardial protective effect of ulinastatin against ischemia/reperfusion injury during open heart surgery with cardiopulmonary bypass].
To investigate the protective effect of ulinastatin on myocardium against ischemia-reperfusion injury in open heart surgery with cardiopulmonary bypass (CPB). ⋯ Ulinastatin effectively protects myocardium from ischemia-reperfusion injury during open heart surgery with CPB.
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Zhonghua yi xue za zhi · Jul 2003
Comparative Study[The influences of propofol on different kinds of brain injuries in rat brain slices].
To investigate the effects of propofol on the three kinds of brain injuries induced by metabolic disorder, neurotoxicity of excitatory amino acid, and oxygen-derived free radicals in rat cerebral cortical and hippocampal slices. ⋯ Propofol has a neuroprotective effect against hydrogen peroxide injury at low and middle concentrations. Propofol of low and middle concentrations does not improve the decrease of the value of A(490). however, propofol of high concentration augments the oxygen-glucose deprivation and glutamate injuries both in the rat cerebral cortical slices and hippocampal slices.
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Zhonghua yi xue za zhi · Jun 2003
[Antineutrophil cytoplasmic antibody associated vasculitis induced by antithyroid agents].
To investigate the significance of antineutrophil cytoplasmic antibody (ANCA) in hyperthyroidism at different stages and treated with different drugs and to investigate the relationship between the ANCA specific target antigens and the clinical manifestations of vasculitis. ⋯ PTU is associated with the production of ANCA in patients with hyperthyroidism. PTU induced ANCA is caused by polyclonal activation of B cells. Anti-MPO antibody may be related to the occurrence of clinical vasculitis.
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Zhonghua yi xue za zhi · Jun 2003
[Application of diffusion-weighted and perfusion magnetic resonance imaging in definition of the ischemic penumbra in hyperacute cerebral infarction].
To investigate the value of diffusion-weighted imaging (DWI) and perfusion imaging (PI) in definition of the ischemic penumbra in hyperacute cerebral infarction. ⋯ Combination of DWI and PI clearly defines the ischemic penumbra in hyperacute stroke patient, thus laying, thus laying a basis for therapeutic intervention plan for stroke patients.