Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Jun 1992
[Clinical study on the prevention of kernicterus caused by hereditary glucose-6-phosphate dehydrogenase deficiency].
A combined preventive scheme was conducted in four hospitals in Guangzhou to lower the rate of kernicterus and mental retardation caused by related neonatal jaundice due to G6PD deficiency. Observation was focused on 330 G6PD deficient infants, and the effects were measured according to the incidence of hyperbilirubinemia and kernicterus. The results, as compared to those of a retrospective study, showed that the incidence of hyperbilirubinemia was significantly decreased (51.4% to 21.2%), and neither kernicterus nor mental retardation infant was found in this series (12.5% in the control group). The authors conclude that this combined scheme is extremely effective and can be used in any large population area in which there is a high gene frequency of G6PD deficiency.
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Zhonghua yi xue za zhi · Oct 1990
[Diagnosis of fetal urinary tract deformity and its early surgical treatment].
From July 1987 to August 1989, ultrasound scan was performed in 419 cases of 24-42-week gestation. The result of antepartum diagnosis showed 12 cases of anomaly (7 males and 5 females). After birth, they were all confirmed by pediatric surgery. ⋯ The lowest operative age was nine days, and the average age was 72 days. It shows that The operative indications were: (1) increased excretory rate of RBC and WBC; (2) functional damage of tube of kidney; (3) decreased serum albumin and metabolic acidosis; (4) bacteriuria and pyouria; (5) absence of general complications (6) pyelocalicectasis was at least three times that of the healthy side; (7) obstruction of the low urinary tract and or bladder-rectum fistula. Early surgical management is important for eugenic development of the infants.
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Zhonghua yi xue za zhi · Jun 1989
[Hemodynamic changes and their relationship with the renin-angiotensin-aldosterone system in chronic obstructive pulmonary disease].
The hemodynamic changes and plasma renin activity (PRA), angiotensin II (ATII), aldosterone (Ald) levels in 38 COPD patients with or without pulmonary hypertension were studied. We found that the right ventricular pressure (RVP), pulmonary artery pressure (PAP), pulmonary vascular resistance (PVR) and the levels of PRA, ATII, Ald increased significantly in patients with pulmonary hypertension when compared with those not accompanied by pulmonary hypertension. ⋯ The relationship between ATII and PAP was very remarkable (r = 0.67, P less than 0.001). These findings suggest that the activation of renin-angiotensin-aldosterone system (RAAS) increases in COPD patients with pulmonary hypertension, and may involve in the development of pulmonary hemodynamic changes.