Regional anesthesia
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Regional anesthesia · Jan 1991
Randomized Controlled Trial Clinical TrialAnalgesic efficacy of low doses of intravenously administered lidocaine on experimental laser-induced pain: a placebo controlled study.
The analgesic efficacy of low doses of intravenously administered lidocaine on experimental laser-induced pain was studied. Lidocaine or placebo was infused intravenously in ten healthy volunteers on 2 separate days according to a double-blind, randomized, cross-over design. Analgesia was assessed by argon laser-induced sensory and pain thresholds and pain evoked potentials after doses of 0.7, 1.85 and 3.7 mg/kg of lidocaine, infused over 15, 45 and 75 minutes, respectively. ⋯ Although administration of the highest dose of lidocaine (mean plasma concentration, 8.5 mumol/l) caused significant increases in pain and sensory thresholds, the magnitude of these increases was no greater than those that occurred during placebo infusion. The power of the pain evoked potentials was significantly decreased by the highest dose of lidocaine (p = 0.0024) compared with placebo. These results probably reflect that the effect of lidocaine on subjective pain perception might be caused primarily by sedation.
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Regional anesthesia · Jan 1991
Randomized Controlled Trial Comparative Study Clinical TrialPostoperative pain treatment after open knee surgery: continuous lumbar plexus block with bupivacaine versus epidural morphine.
The anesthetic and side effects of a continuous lumbar plexus block ("3-in-1" block) were compared with that of epidurally administered morphine after open knee surgery. Twenty-two patients were randomized into two groups in this prospective, double-blind study. At the end of surgery, catheters were inserted for all the patients into both the femoral nerve sheath and the epidural space. ⋯ The pain scores and supplemental morphine consumption were low in both groups and did not differ significantly. Lumbar plexus block produced a statistically significant a lower incidence of nausea, vomiting, pruritus and urinary retention. Although no significant differences in pain relief were shown between the two methods, we conclude that postoperative lumbar plexus block is preferable for postoperative pain relief because there is a lower frequency of side effects.
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Regional anesthesia · Jan 1991
Randomized Controlled Trial Clinical TrialPostoperative pain relief in children from the parascalene injection technique.
Nineteen pediatric patients aged 6 months to 12 years scheduled for elective upper extremity surgery were randomly assigned to receive either a parascalene block or sham injection. Both groups received a potent inhalational agent for operative anesthesia. ⋯ Patients in the parascalene group had superior postoperative analgesia, as evidenced by significantly less opioid requirement in the first 12 postoperative hours and by significantly lower scores on an objective pain scale. We found the parascalene approach to the brachial plexus a simple and reliable analgesic technique in anesthetized children.
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Regional anesthesia · Jan 1991
Randomized Controlled Trial Clinical TrialContinuous spinal anesthesia with hyperbaric bupivacaine: a dose-response analysis.
Continuous spinal anesthesia (CSA) with hyperbaric bupivacaine (0.75% bupivacaine in 8.25% dextrose and water) was administered to 27 adult males for transurethral endoscopic surgery. Patients were randomized to receive either 3.75, 7.5 or 10 mg hyperbaric bupivacaine in a double-blind fashion. A 20-gauge nylon catheter was inserted at the L3-4 interspace, via an 18-gauge Tuohy-Schliff needle, extending only 2 cm into the subarachnoid space. ⋯ The role of the subarachnoid catheter in the dispersion and distribution of bupivacaine within the subarachnoid space was studied in a model spinal canal system and compared with the distribution of bupivacaine administered via a standard 25-gauge spinal needle. No significant differences were found in the distribution of bupivacaine with either method of injection. The distribution of hyperbaric bupivacaine within the subarachnoid space appears to be related to baricity but is unrelated to administration via needle or catheter.
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Regional anesthesia · Jan 1991
Vertebral column length and spread of hyperbaric subarachnoid bupivacaine in the term parturient.
Patient height is considered an important determinant of the dose of spinal anesthesia. However, the relationship between body height and the level of sensory anesthesia with a fixed dose of spinal anesthetic has not been clearly documented. Recent evidence suggests no correlation between height or weight of parturients and spread of spinal anesthesia. ⋯ We studied the correlation between vertebral length measured from C7 to the level of the iliac crest (IC) and to the sacral hiatus (SH) and the sensory anesthetic level after the subarachnoid administration of 12 mg hyperbaric bupivacaine in term pregnant patients. There was no correlation between patient height, weight or body mass index and sensory anesthesia level. However, a significant correlation existed between vertebral length measured from C7 to IC (r = 0.32, p = 0.025) or to SH (r = 0.38, p = 0.006) and the level of anesthesia.