Przegla̧d lekarski
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Endogenous evoked potentials (P300) are elicited by several stimuli, and are electrophysiological consequence of cognitive processing. Abnormalities have often been reported in dementive syndromes, demyelinating diseases, metabolic disorders, CNS tumors, phacomatoses, neuroinfections, attention deficit hyperactivity disorder and epilepsy. The role of this element of neurophysiological characteristics is debated in migraine, pato-genetically undefined, and other primary headaches. ⋯ The findings of shortened latency of P300 potentials in children with migraine, esp. migraine with aura may contribute to migraine pathogenesis. There were no significant differences in the latency and amplitude of P300 potentials in children with migraine without aura compared with the frequent ETTH. This finding does not add further information to the differentiation of both types of primary headaches.
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The case of a 58-year old patient, who nearly experienced cardiac arrest due to growing oxygen deficiency, was presented. The arrest was brought about by the impossibility to perform endotracheal intubation. A laryngeal mask successfully replaced an intubation tube and enabled artificial lung ventilation and restoration of correct blood oxygenation.
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Contemporary treatment of cancer (intensive chemotherapy, radiotherapy, radical surgery, stem cell transplantation) and severe non-neoplastic blood diseases resulted in significant improvement of treatment results. Currently over 70% of children with cancer can be cured. However, at the same time number of severe complications, including life-threatening infections began to increase. ⋯ Our presentation will review currently available antifungal drugs and guidelines for treatment of specific fungal infections. The plan of antifungal treatment must include not only the species of fungal pathogen, but also the site and extent of infection, as well as patient status, including stage of primary disease, previous therapy and previous organ damage. Rational management would allow to choose appropriate antifungal drug, optimize dosage and duration of treatment and estimated costs, and above all to improve the chance to effectively control the life-threatening fungal infections.
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Randomized Controlled Trial Clinical Trial
[The effect of vitamin, macro and microelement supplementation on markers of iron status in blood of pregnant women].
Interest in assessing iron status in the population of women during their child-bearing age has grown recently both in terms of detecting iron stores and evaluating whether they are sufficient to meet increasing needs during pregnancy. The fact that iron deficiency anaemia often develops in pregnancy indicates that that iron stores and dietary iron are insufficient to requirements and iron supplementation is needed. The aim of the present study was to determine the effect of vitamin, macro and microelement supplementation on iron status of pregnant women and of their newborns. ⋯ In serum of umbilical cord blood concentration of total iron, transferin and ferritin were similar in newborns of both groups of mothers. The above results suggested that vitamin, macro and microelement supplementation of pregnant women improved iron status in mothers and in their children. It seems that administration Vibovitmama formula can be recommended as a dietary supplement in pregnancy in order to prevent subclinical deficiency of iron.
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A large number of publications, primarily clinical studies, demonstrate the increasing use of procalcitonin (PCT) in modern clinical practice. PCT is a propeptide of calcitonin induced by a variety of stimuli including bacterial endotoxins, proinflammatory cytokines and triggering events such as trauma or cardiogenic shock. PCT is not or only slightly induced by viral infections, autoimmune disorders, neoplastic diseases and organs transplantation. The aim of this study was to evaluate the usefulness of PCT as a diagnostic and prognostic tool in patients for early differentiation between bacterial and nonbacterial infection origin.