Przegla̧d lekarski
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The occurrence of the disturbances of oropharyngeal phases of swallowing in Amyotrophic Lateral Sclerosis (ALS) patients has been well documented. ⋯ This study reveal the occurrence of disturbances of the oesophageal phase of swallowing in ALS patients with dysphagia.
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Clinical Trial
[Mycophenolate mofetil in treatment of childhood nephrotic syndrome--preliminary report].
The management of nephrotic syndrome (NS) in children remains a clinical challenge for pediatricians and pediatric nephrologists. Especially, the treatment of patients with steroid-resistant (SR) and steroid-dependent (SD) nephrotic syndrome, because they are at risk for developing complications from prolonged exposure to steroids, CsA and alkylating agents. Mycophenolate mofetil (MMF) is a selective and reversible inhibitor of inosine monophosphate dehydrogenase used above all in transplantology and recently also in patients with nephrotic syndrome. ⋯ The initial clinical observation of MMF treatment in nephrotic patients shows its best effect in the group of patients with steroid-dependent NS. MMF can safely be used in children with NS. The introduction of MMF allows for reduction of other chronically used medications, especially CsA and steroids.
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Comparative Study
[Assessment of chosen cognitive functions in children and adolescents with primary headaches].
Foundations and aim of the study: Right development of cognitive functions is one of the basal factors, which determines good realization of the developmental tasks, for example achievement in education. Primary headaches especially migraine can be one of the important factor disturbing cognitive functioning of children and adolescents. The aim of the study was to estimate the level of some chosen aspects of cognitive and intellectual functioning of children and adolescents with primary headaches: migraine and tension type (TTH). ⋯ Patients with migraine in comparison to children with TTH show important disturbances in ability of short-term visual memory and visuomotor integration. Diagnosed selected cognitive dysfunctions in children with primary headaches can disturb accomplishment of tasks connected with education but they do not have any important influence on general intellectual functioning.
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Although much more about the safe and effective management of pain in children is now known, this knowledge has not been widely or effectively translated into routine clinical practice. Pain in children is still a big problem even thought available many possibilities to cure it. Malpractice during postoperative period influence not only for recovery, but also causes long lasting consequences (emotional changes). ⋯ Laryngological procedures in children cause a severe pain. The most common procedure in children in laryngological practice is adenotomy. There is a pressing need for further research and clinical development in the management of pain in children.
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The mixed irritable bowel syndrome (IBS) is a functional disorder concerned with diarrhea and constipation without organic changes. The etiology of IBS is complex, concerning with the changing psychological factors and associated with the autonomic dysfunction ultimately. The aim of the study was the estimation of the autonomic nervous system (ANS) activity in IBS patients using time and frequency domain analysis parameters of heart rate variability. ⋯ Our results indicate changes of the circadian ANS activity in patients with mixed IBS: the increase of the parasympathetic and the decrease of the sympathetic activity. However the ANS response to parasympathetic stimulation in DB test was diminished.