Revista brasileira de anestesiologia
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Rev Bras Anestesiol · Feb 2003
[Exercise-induced rhabdomyolysis and risk for malignant hyperthermia: case report.].
Rhabdomyolysis is a skeletal muscle injury with cell components' release to plasma. Exhaustive exercise, especially in non-conditioned individuals, may result in severe morbidity such as hyperkalemia, metabolic acidosis, disseminated intravascular coagulation, acute respiratory distress syndrome and rhabdomyolysis. It has been suggested that malignant hyperthermia, thermal shock and exercise-induced rhabdomyolysis are closely related syndromes. This report aimed at describing a case of fatal rhabdomyolysis after physical exercise and its correlation with malignant hyperthermia. ⋯ It has been suggested that malignant hyperthermia and exercise-induced rhabdomyolysis are closely related syndromes. Patient died before any specific investigation of malignant hyperthermia, but it is important to look for susceptibility for this syndrome within the family to avoid potentially life-threatening anesthetic events.
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Rev Bras Anestesiol · Feb 2003
[Total intravenous anesthesia for thymectomy in a Myasthenia Gravis patient: case report.].
Patients with neuromuscular diseases, as Myasthenia Gravis, react abnormally to anesthetics, depending on the technique and on the drugs. This report aimed at showing a case of Myasthenia Gravis patient submitted to thymectomy under total intravenous anesthesia with propofol and remifentanil. ⋯ Total intravenous anesthesia, with short-lasting anesthetics without active metabolites has favored recovery and early extubation of a Myasthenia Gravis patient submitted to thymectomy.
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Dexmedetomidine is a new alpha2-adrenergic agonist with a selectivity ratio of 1600:1 (alpha2:alpha1). It has important sedative and analgesic effects, good hemodynamic control at stress situations and may, by itself, induce anesthesia. This drug has been used to promote postoperative and intensive care sedation and analgesia. Due to such properties, dexmedetomidine has recently become a co adjuvant drug for anesthesia. So, this is a review of the literature about dexmedetomidine in anesthesia. ⋯ Dexmedetomidine premedication, infusion during anesthesia or in the postoperative period improves hemodynamic stability. Anesthetic consumption is decreased during anesthesia. Patients sedated with dexmedetomidine may awake, when requested and become cooperative. Even high dexmedetomidine doses do not cause respiratory depression. Bradycardia is a frequent side effect which may be minimized by slow drug infusion. So, dexmedetomidine is an important additional resource to anesthetic practice that may be used in different patients and surgical procedures.
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Rev Bras Anestesiol · Feb 2003
[Evaluation of maternal acid-base status after different doses of spinal sufentanil for cesarean section and its effects on the neonates.].
Spinal sufentanil in obstetric anesthesia promotes immediate pain relief, improves anesthesia quality and prolongs postoperative analgesia, its major side effect being respiratory depression. This study aimed at evaluating maternal acid-base status after different doses of spinal sufentanil associated to hyperbaric bupivacaine for cesarean section, and its effects on neonates' vitality. ⋯ The association of spinal hyperbaric 0.5% bupivacaine to low sufentanil doses has shown to be safe to both mother and neonate, preserving their hemodynamic and acid-base status.
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Rev Bras Anestesiol · Feb 2003
[Priming versus bolus: a comparative study with different cisatracurium doses.].
The priming technique is an alternative to shorten nondepolarizing neuromuscular blockers onset time. This study aimed at evaluating maximum neuromuscular block onset, tracheal intubation conditions and cardiocirculatory changes determined by different cisatracurium single or fractional doses. ⋯ Fractional cisatracurium doses have not shortened maximum neuromuscular block onset as compared to bolus injections. They have however produced acceptable tracheal intubation conditions without cardiovascular changes.