Casopís lékar̆ů c̆eských
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Casopís lékar̆ů c̆eských · Aug 1989
[Prevention of recurrent urinary infections using Solco Urovac, a polymicrobial vaccine].
The administration of Solco Urovac polymicrobial vaccine to 26 patients with recurrent episodes of urinary tract infection significantly reduced the number of episodes, in one third of the persons even prevented them for a period of one year. In case of persistent bacteriuria, accompanying, for example, nephrolithiasis, the vaccine had no effect. A better effect can be achieved in cases of uncomplicated infections of the lower urinary tract than in infections associated with structural abnormalities of the kidneys and urinary tract. In some patients, the administration of the vaccine is accompanied by mild side effects which, but only exceptionally, can lead to the discontinuation of the therapy.
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Casopís lékar̆ů c̆eských · Aug 1989
[Differences in patient sensitivity to currently used non-depolarized curaremimetics and factors which affect it].
A whole number of factors which affect the depth as well as duration of the block after administration of non-depolarizing myorelaxants, both positively and negatively. However, the effect in one patient can be predicted only with difficulty--as this paper showed--as neither the hydration level, age nor kalemia concentration had any effect on the depth of the neuromuscular block. Neither in patients, otherwise healthy, is it possible to predict the degree of the neuromuscular block after administering a standard dose of curaremimetic. ⋯ The determination of the actual block depth can help to control relaxation according to the needs of the surgeon or anaesthesiologist, and according to the individual patient's sensibility. A different sensibility response to myorelaxants was found in pipecuronium, vecuronium and even in atracurium. It corresponds approximately to gaussian curve of frequency.