Biulleten' eksperimental'noĭ biologii i meditsiny
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Biull Eksp Biol Med · Jul 1986
[Evaluation of the efficacy of extracorporeal membrane oxygenation of animals with acute respiratory insufficiency].
The efficiency of extracorporeal membrane oxygenation was studied for 2-3 hours in experiments on dogs with severe ventilatory respiratory failure. Extracorporeal oxygenation led to the decrease in arterial hypoxaemia and hypercapnia in animals. ⋯ At the same time during veno-arterial perfusion oxygen delivery provided by the cardiac output decreased almost two-fold by the second hour of perfusion. This might be the reason for inadequate oxygen delivery to the brain and heart. 67% and 71% of animals survived after veno-arterial and veno-venous perfusion, respectively.