Archives of pediatrics & adolescent medicine
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Arch Pediatr Adolesc Med · Oct 2008
Multicenter Study Comparative StudyInfluenza vaccine effectiveness among children 6 to 59 months of age during 2 influenza seasons: a case-cohort study.
To measure vaccine effectiveness (VE) in preventing influenza-related health care visits among children aged 6 to 59 months during 2 consecutive influenza seasons. ⋯ In 2 seasons with suboptimal antigenic match between vaccines and circulating strains, we could not demonstrate VE in preventing influenza-related inpatient/ED or outpatient visits in children younger than 5 years. Further study is needed during years with good vaccine match.