JPMA. The Journal of the Pakistan Medical Association
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The red cell distribution width (RDW) is an index of the variation in red cells size (anisocytosis). A study was conducted to examine the validity of using RDW in improving classification of microcytic anaemias. A total of 300 blood samples collected from a patient population aged 3 months to 55 years who were referred for haemoglobin electrophoresis were examined at the Aga Khan University Hospital (AKUH). ⋯ Also, of the 82 thalassemia minor, 28 patients had normal haemoglobin level, of which 6 had elevated RDW and of the 54 with low haemoglobin level, 35 had elevated RDW. RDW was normal in 41 patients with thalassemia minor trait. Our results suggest that RDW alone cannot be used as a reliable indicator to distinguish between thalassemia minor and other causes of microcytosis.