JPMA. The Journal of the Pakistan Medical Association
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HLA Antigen A, B and DR frequencies were determined in 912 subjects who were prospective donors and recipients for renal transplantation. Of the 912, 305 were Sindhi, 248 Punjabi, 315 Urdu and 44 Pushto speaking. HLA A1, A2, A11 and A19 were common in all these groups. ⋯ DR6 (13) in Sindhi, Urdu and Pushto and DR6 (14) in Punjabi, DR5 (11) in Urdu, Punjabi and Pushto speaking subjects. Overall, Pakistani frequencies showed linkage to Caucasians and Orientals. This paper describes differences in frequencies in various population groups within Pakistan which may have relevance in factors where HLA system plays a crucial role.