JPMA. The Journal of the Pakistan Medical Association
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Poisoning has reported to be a major cause of death and burden of disease in low- and middle-Income countries. Rhabdomyolysis is a common consequence of many poisoning cases and serum creatine phosphokinase (CPK) is a marker for it. The aim of the study was to assess whether the admission creatine phosphokinase in comatose patients with acute poisoning is a predictive factor for the treatment outcome. ⋯ We concluded that the admission serum CPK level for a poisoned patient, seems to be an acceptable predictor for the outcome in poisoned patients. Further studies are still needed.
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Acute renal failure refers to sudden deterioration in biochemical and physiological functioning of kidneys and often associated with multi organ failure. Continuous renal replacement therapy (CRRT) holds special significance for the treatment of renal failure due to a variety of factors. It is believed that CRRT helps in restoration of acid-base imbalances and electrolyte abnormalities. ⋯ Besides this, several studies have supported that CRRT enables practitioners to adjust drug dosages and prevent drug accumulation and overdose. In addition, gradual removal of solutes and metabolic waste products helps to clear inflammatory mediators and ensure adequate nutrition for patients and lead to improved renal recovery. Therefore, this article will discuss the different treatment modalities that encompass CRRT and explore the indications and advantages of CRRT in acute renal failure.
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Randomized Controlled Trial
Effects of aminophyllinein preventing renal failure in premature neonates with asphyxia in Isfahan-Iran.
Considering the relation between prematurity andasphyxia and also renal failure in neonates, the aim of this study was to determine the effect of aminophyllinein urine and serum indices of renal failure and consequently its prevention, in Premature Infants with asphyxia in Esfahan-lran. ⋯ Aminophylline could prevent renal dysfunction in preterm neonates with asphyxia. Neonates who received aminophylin on the first day of life indicated a significant improvement in GFR and urine output.
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In educational hospitals, in addition to providing care, emergency medicine department plays an important role in providing education and increasing the quality of care and education. This study was an endeavor to evaluate the performance of emergency medicine department in different areas such as education, service provision and interaction with other departments. ⋯ The results of the emergency department evaluation by different groups as well as indices showing the performance of this department revealed its overall performance in educational, clinical, and interactional areas as good. The findings of this study can be applied in Alzahra Hospital to promote the positive points and amend the negative points.
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To determine the frequency, types (disease states) and outcome of severe obstetric morbidity in patients presenting at a public-sector tertiary care hospital. ⋯ Haemorrhage, hypertensive disorders and ruptured uterus were the leading causes of obstetric near-miss, whereas sepsis, acute fatty liver of pregnancy and peripartum cardiomyopathy resulted in the highest case fatalities.