JPMA. The Journal of the Pakistan Medical Association
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Randomized Controlled Trial Comparative Study
Comparison of efficacy and safety of topiramate with gabapentin in migraine prophylaxis: randomized open label control trial.
To compare the efficacy and safety of topiramate with gabapentin in the prophylaxis of migraine patients. ⋯ Gabapentin appeared well tolerated in 30 (75%) patients compared to topiramate in 23(57.5%) patients. Both drugs were equally effective in migraine prophylaxis.
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To evaluate the incidence of complications, morbidity and mortality, and the associated risk factors with mortality at a Paediatric Cardiology Intensiv Care Unit of a developing country. ⋯ Critically ill cyanotic young infants in the first 24 hours after operation experienced high mortality. Prolonged mechanical ventilation was also associated with high mortality.
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To evaluate the current practices regarding formal or informal implementation of individual elements of the World Health Organisation's Surgical Safety Checklist in tertiary care hospitals of Karachi and to establish a pre-checklist baseline to suggest a plan for implementation of the checklist. ⋯ The results suggest that the safety of surgical patients in the operating theaters in hospitals under review was far from satisfactory. Introduction of and adherence to a safety checklist would result in significant reduction in death and complication rate.