Journal of accident & emergency medicine
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Review Comparative Study
Thrombolysis in acute myocardial infarction: analysis of studies comparing accelerated t-PA and streptokinase.
To compare outcomes from accelerated alteplase (recombinant tissue plasminogen activator, t-PA) and streptokinase use in acute myocardial infarction. ⋯ The data do not consistently show a 30 day mortality benefit from using t-PA compared with streptokinase in acute myocardial infarction, but do show increased risk of stroke. Streptokinase can be considered the thrombolytic agent of choice.