Studies in health technology and informatics
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Stud Health Technol Inform · Jan 2006
Integrating medical and genomic data: a successful example for rare diseases.
The recent advances on genomics and proteomics research bring up a significant grow on the information that is publicly available. However, navigating through genetic and bioinformatics databases can be a too complex and unproductive task for a primary care physician. In this paper we present diseasecard, a web portal for rare disease that provides transparently to the user a virtually integration of distributed and heterogeneous information.
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Stud Health Technol Inform · Jan 2006
A Markov model to describe daily changes in organ failure for patients at the ICU.
As the support and stabilization of organ function is a major goal of treatment in the Intensive Care Unit (ICU), changes in the function of organ systems are an important indicator of the progression of the disease and recovery. This paper presents how to construct a model that describes changes in organ failure of ICU patients on a day-to-day basis. ⋯ The joint set of equations, extended with equations for predicting ICU discharge and death, constitutes a firstorder multivariate Markov model. We applied the procedure on a dataset and found that most types of organ failure are highly persistent.
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Stud Health Technol Inform · Jan 2006
Relation between the sagittal pelvic and lumbar spine geometries following surgical correction of adolescent idiopathic scoliosis: a preliminary study.
The influence of surgery on the relationship between the lumbar spine and the pelvis in adolescent idiopathic scoliosis (AIS) remains mostly unknown. The sagittal spinopelvic balance of 40 patients with AIS undergoing posterior spinal instrumentation and fusion was studied. After surgery, the total lumbar lordosis (LL) and the LL below fusion remained correlated to the sagittal pelvic geometry. ⋯ This preliminary study shows that pelvic morphology probably has an important impact on the postoperative sagittal lumbar alignment. Evaluation of the sagittal pelvic geometry could therefore be useful in the preoperative planning of surgery for AIS. Further studies with more patients are still needed in order to confirm this hypothesis and to evaluate if the distal fusion level influences the spino-pelvic balance.
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Stud Health Technol Inform · Jan 2006
Soprano Specialty Forms Project--A solution that empowers clinicians in the management of research and audit data.
Throughout the world, clinicians (including nurses) create ad-hoc stand-alone databases in order to meet their individual research and audit requirements. These databases often exist in large numbers within an institution. ⋯ The Soprano Specialty Forms solution developed by Orion Health in collaboration with Auckland District Health Board resolves this problem. The solution provides a common data storage and coding infrastructure within which clinicians can create their own forms for data collection, enter data through an integrated portal used as part of their everyday clinical practice, and easily query the data collected regardless of its source.
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Stud Health Technol Inform · Jan 2006
Timing of osteotomy for thoracolumabar or lumbar kyphosis secondary to ankylosing spondylitis.
Ankylosing spondylitis may lead to a rigid thoracolumbar kyphotic deformity. Several authors have reported the results of patients treated by a lumbar osteotomy, but there is no consensus on the level of the osteotomy and on timing of osteotomy. The purpose of this study is to explore timing of osteotomy for thoracolumabar or lumbar kyphosis secondary to ankylosing spondylitis by analyzing the natural history of 78 AS patients. ⋯ Lumbar pain arrests for more than 6 months (exclusive of mechanical pain of lumbar), normal blood sedimentation rate continues for two times, and reactive protein is negative. These factors must be considered in timing of osteotomy for thoracolumabar or lumbar kyphosis secondary to ankylosing spondylitis.