Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
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Zhongguo Yi Xue Ke Xue Yuan Xue Bao · Feb 2003
Review[Recent advances in islet transplantation and pancreatic stem cell research].
This paper reviewed recent advances in pancreatic islet transplantation research, including islet isolation, purification, culture, cryopreservation and immunoisolation. Latest progresses in induction of pancreatic stem cell and embryonic stem cell to differentiate into insulin-producing islets were also introduced. On the basis of the present situation and future development of islet transplantation-based therapies for diabetes, the author thought that allogeous islet transplantation is a main choice for type I diabetes today and pancreatic stem cell transplantation for tomorrow.
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Zhongguo Yi Xue Ke Xue Yuan Xue Bao · Feb 2003
[Diagnosis and treatment of Paget's disease of the breast: report of 33 cases].
To study the clinical features and histologic criteria of Paget's disease of breast, and evaluate the potential prognostic factors for better appropriate treatment strategies. ⋯ Most patients with Paget's disease had associated breast carcinoma. Paget's disease of the breast with a palpable breast mass is more likely to be accompanied by an invasive ductal carcinoma and had a poor prognosis. Patients with any nipple complaints deserve a serious investigation.
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Zhongguo Yi Xue Ke Xue Yuan Xue Bao · Feb 2003
[The method of accelerating osteanagenesis and revascularization of tissue engineered bone in big animal in vivo].
To study whether tissue engineered bone can repair the large segment bone defect of large animal or not. To observe what character the fascia flap played during the osteanagenesis and revascularization process of tissue engineered bone. ⋯ The model of 2 cm caprine tibia diaphyseal defect cannot be repaired by goat itself and can satisfy the tissue engineering's demands. Tissue engineered bone had good ability to repair large segment tibia defect of goat. Fascia flap can accelerate the revascularization process of tissue engineered bone. And by this way, it augment the ability of tissue engineered bone to repair the large bone defect of goat.