Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
-
Zhongguo Yi Xue Ke Xue Yuan Xue Bao · Feb 2015
Effects of MicroRNA-132 transfection on the proliferation and apoptosis of human liver cancer cells in vitro and in vivo.
To observe the biological role and underlying mechanism of microRNA-132 (miR-132) in liver cancer cell proliferation and apoptosis. ⋯ miR-132 is down-regulated in human liver cancer tissues miR-132 transfection can effectively inhibit proliferation and promote apoptosis of MHCC97H cells in vitro and in vivo. Therefore, miR-132 may become a new target in liver cancer treatment.