The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique
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Can J Clin Pharmacol · Jan 2001
Improving prescribing in the elderly: a study in the long term care setting.
To determine the prevalence and predictors of potentially inappropriate prescribing of medications in the long term care setting, and to determine the effectiveness of follow-up pharmacist letters to the prescribing physicians in improving prescribing. ⋯ Potentially inappropriate prescribing in the long term care setting is common and can be improved by the provision of a follow-up letter suggesting safer alternatives.
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Can J Clin Pharmacol · Jan 2001
Case ReportsMetformin-associated lactic acidosis in a low risk patient.
Metformin is an oral hypoglycemic agent belonging to the class of biguanides that are commonly used in the treatment of type II diabetes mellitus. Lactic acidosis is a rare but severe adverse reaction that occurs primarily in patients with contraindications such as renal failure. ⋯ The present case report shows that metformin-associated lactic acidosis can occur in patients without pre-existing renal insufficiency. Metformin should be temporarily stopped when acute renal failure occurs or is anticipated.