Gan to kagaku ryoho. Cancer & chemotherapy
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Gan To Kagaku Ryoho · Jan 2000
Review[A summary report of response evaluation criteria in solid tumors (RECIST criteria)].
The World Health Organization definitions for objective tumor response published in the 1979 WHO Handbook have been the most commonly used criteria around the world. However, some problems developed with the use of WHO criteria. ⋯ A revised version of the WHO criteria, Response Evaluation Criteria in Solid Tumors (RECIST criteria), was published in 1999 to deal with these issues. However, some problems concerning the evaluation of non-cytotoxic drugs and unidimensional measurements remain in the new criteria.
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There is often little foundation for decisions in experience-based or impression-based medicine. Therapy, however, should be based on the highest level of available evidence. In many clinical cancer practices, "uncertainty" exists. ⋯ There is no combination therapy including a new anti-cancer agent which can be recommended as a "gold standard". There is no current evidence that either confirms or refutes non-platinum-based combination chemotherapy. Second line chemotherapy Second line chemotherapy (docetaxel 75 mg/m2) improves survival in patients previously treated with platinum-based chemotherapy.