Gan to kagaku ryoho. Cancer & chemotherapy
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To provide effective and safe cancer treatment, the medical staff must form a team with patients and their family. Pharmacists have to be responsible for verifying chemotherapy prescription orders, mixing of anticancer drugs, management of adverse drug reactions, patient education, while providing drug information and participation in palliative care. To promote pharmacists who have acquired advanced knowledge and skills, The Japanese Society of Hospital Pharmacists started and educational program and established the certification of board-certified oncology pharmacy specialists (BCOPS) and board-certified pharmacists in oncology pharmacy (BCPOP). As of November 2007, 56 pharmacists were qualified as BCOPS.
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Gan To Kagaku Ryoho · Apr 2008
[Usefulness of perospirone for the prevention of nausea related to opioid administration].
In our department, prochlorperazine, a D2 receptor antagonist, was previously administered to prevent nausea related to the introduction of opioids. However, we always had to consider extrapyramidal symptoms. Since August 2006, perospirone has been administered to all patients who have commenced oral opioid therapy, to prevent nausea. In this study, we investigated its usefulness in the prevention of nausea. ⋯ These results suggest the usefulness of perospirone for the prevention of nausea related to the intro- duction of opioids.
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Gan To Kagaku Ryoho · Apr 2008
[Long- and short-term survivors after chemotherapy among patients with advanced or recurrent gastric cancer in our hospital].
Since S-1 was approved in 1999, the response rate and the disease control rate of this chemotherapy for advanced or recurrent gastric cancer has been improved. Aa a result, we can plan for chemotherapy in patients with advanced or recurrent gastric cancer, because the median survival time (MST) with advanced or recurrent gastric cancer was over 20 months. ⋯ In patients with only recurrent gastric cancer, the interval from surgery to recurrence is a significant prognostic factor. We thus show the results of chemotherapy for advanced or recurrent gastric cancer in our hospital and the characteristic findings in long- and short-term survivors for chemotherapy, and discuss effective planning of chemotherapy for each patient with advanced or recurrent gastric cancer.