Gan to kagaku ryoho. Cancer & chemotherapy
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Gan To Kagaku Ryoho · May 2011
Assessment of dyspnea in terminally ill cancer patients: role of the thoracic surgeon as a palliative care physician.
Many cancer patients suffer from rapidly-progressing dyspnea that is difficult to relieve. ⋯ Palliative care physicians who specialize in the respiratory system can, to some extent, predict the occurrence of rapidly progressive dyspnea in cancer patients. It is important to explain the methods of relieving dyspnea to the patient, the patient's family, and the oncologist early, so that decisions on how to manage dyspnea can be made in advance.
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After the introduction of imatinib, the outcome for patients with advanced gastro-intestinal stromal tumor (GIST) was vastly improved. However, resistance to imatinib has become a new problem. ⋯ Sunitinib is the first drug that showed an effectiveness for treating GIST refractory to imatinib. New molecular target drugs for overcoming imatinib resistance are being developed now.