Lijec̆nic̆ki vjesnik
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Lijec̆nic̆ki vjesnik · May 2009
Review[The role of taxanes in breast cancer chemotherapy: what's new 15 years after?].
Taxanes were established as leading drugs in chemotherapy of breast cancer. In the first line chemotherapy of advanced disease taxanes were combined with other cytostatics. Taxane-based combinations in comparison with taxanes in sequential use were observed. ⋯ Paclitaxel is treatment schedule dependent, because its weekly administration setting may result in better treatment outcome. Docetaxel may be more effective if given every 3 weeks rather than weekly. Targeted therapy in combination with taxanes improves survival rate in adjuvant setting as in advanced disease.