Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
Automation in anesthesia: computer controlled propofol infusion and data acquisition.
This work presents the improvement of a software for a clinical setup, the Anesthesia Synchronization Software (ASYS). The first version presented the data acquisition from cerebral monitors and a partial control with Target Controlled Infusion (TCI) system. Based on pharmacokinetic models, the effect-site and plasma concentrations can be related with the drug dose infused and vice versa. This later version comes with the implementation of the hemodynamic monitor always present in operating rooms and with the full TCI system developed to determine the infusion rates of the drug which are given as commands to the infusion pumps.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
Model predictive control of depth of anaesthesia: guidelines for controller configuration.
The paper presents a feasibility study on the use of Model based Predictive control (MPC) to regulate the level of Depth of Anaesthesia (DoA) when measured by the BIS index. Pharmacokinetic/pharmacodynamic nonlinear models of DoA when Propofol and Remifentanil are used as hypnotic and analgesic drugs are linearized around the desired working point for DoA in order to obtain a linear state-space model coupled with an extra integrator to include integral action in the control. This state-space model is then used in a MPC algorithm. The main contribution of the paper consists in the characterization of the influence of the different design parameters in the MPC performance when controlling DoA.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
Phase space reconstruction approach for ventricular arrhythmias characterization.
Ventricular arrhythmias, especially tachycardia and fibrillation are one of the main causes of sudden cardiac death. Therefore, the development of methodologies, enable to detect their occurrence and to characterize their time evolution, is of fundamental importance. ⋯ Features from current and previous time windows are provided to a dynamic neural network classifier, enabling arrhythmias detection and evolution trends assessment. Sensitivity and specificity values, evaluated from public MIT-BIH databases, show the effectiveness of the proposed strategy.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
Automatic identification of lumbar level with ultrasound.
An ultrasound-based system is created to label the lumbar vertebrae for the purpose of percutaneous needle insertion. Many lumbar punctures have a preferable vertebral level for needle insertion, but the traditional method of manual palpation is known to be inaccurate for determining the level. Needle insertion for epidural anesthesia in obstetrics is preferably performed at the L3-L4 interspace and miscalculation can lead to complications such as nerve damage and paralysis. ⋯ The vertebrae are labeled with a novel image processing algorithm. Since the coccyx is relatively easy to locate by palpation, the labels of the vertebrae from the panorama can be converted to skin location on the subject. The method is validated against independent measurements by a sonographer.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
Clinical TrialA neuro-fuzzy approach for predicting hemodynamic responses during anesthesia.
The effect of drugs' interaction on the hemo-dynamic variables is of great importance when considering patient's safety and stability. It is also important for control infusion systems during anesthesia. ⋯ The use of subtractive clustering improved the model performance on the testing data set. The fuzzy model is able to capture the synergistic interaction between the two drugs, but other influences were detected.