Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Burst suppression is an electroencephalogram pattern observed in states of severely reduced brain activity, such as general anesthesia, hypothermia and anoxic brain injuries. The burst suppression ratio (BSR), defined as the fraction of EEG spent in suppression per epoch, is the standard quantitative measure used to characterize burst suppression. ⋯ Our approach removes the need to artificially average the ratio over long epochs and allows us to make formal statistical comparisons of burst activity at different time points. Our state-space model suggests a more principled way to analyze this key EEG feature that may offer more informative assessments of its associated brain state.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2011
Long-term performance of a CE-approved telemetric intracranial pressure monitoring.
Telemetric intracranial pressure (ICP) monitoring has been a challenge throughout several decades. Major obstruction was to minimize zero drift of absolute pressure sensors. A new promising product demonstrating in-vitro excellent long-term stability has been tested for its reliability in an animal model with a follow-up of up to 2 years. ⋯ The zero-shift was -1.7 ± 7.6 mm Hg (limits of agreement: 4.4 ± 1.9 mm Hg) and -3.0 ± 6.0 mm Hg (limits of agreement: 3.6 ± 2.6 mm Hg) in STel and PTel respectively meeting well the devices specification of ± 2 mm Hg drift per year. The reliability of both telemetric probes has been proved as quite comparable (p=0.2). These new telemetric ICP probes demonstrate reliable data during at least the first 6 months after implantation.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2011
Closing the loop for Deep Brain Stimulation implants enables personalized healthcare for Parkinson's disease patients.
DEEP brain stimulation implants have improved life quality for more than 70,000 patients world-wide with diseases like Parkinson's, essential tremor, or obsessive-compulsive disorder where pharmaceutical therapies alone could not offer sufficient relief. Still, optimization and monitoring relies heavily on regular clinical visits, putting a burden on patient's comfort and clinicians. Permanent monitoring and combination with other patient health signals could ultimately lead to a personalized closed-loop therapy with remote quality monitoring. This requires technological improvements on the DBS implants such as integration of recording capabilities for brain activity monitoring, active low-power electronics, rechargeable battery technology, and body sensor networks for integration with e.g. gait, speech, and other vital information sensors on the patient's body and a link to a telemedicine platform using mobile technologies.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2011
Snoring analysis for the screening of Sleep Apnea Hypopnea Syndrome with a single-channel device developed using polysomnographic and snoring databases.
Several studies have shown differences in acoustic snoring characteristics between patients with Sleep Apnea-Hypopnea Syndrome (SAHS) and simple snorers. Usually a few manually isolated snores are analyzed, with an emphasis on postapneic snores in SAHS patients. Automatic analysis of snores can provide objective information over a longer period of sleep. ⋯ The system was able to correctly classify 77% of subjects in 4 severity levels, based on snoring analysis and sound-based apnea detection. The sensitivity and specificity of the system, to identify healthy subjects from pathologic patients (mild to severe SAHS), were 83% and 100%, respectively. Besides, the Apnea Index (AI) obtained with the system correlated with the obtained by PSG or Respiratory Polygraphy (RP) (r=0.87, p<0.05).
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Conf Proc IEEE Eng Med Biol Soc · Jan 2011
The impact of various backboard configurations on compression stiffness in a manikin study of CPR.
When performing cardiopulmonary resuscitation (CPR) it is important that adequate back support is given to the patient in order to allow the medical practitioner to produce an appropriate technique during chest compression (CC). The current study investigates how backboard configuration (i.e., orientation and size) impact compression stiffness during CPR using a torso CPR training manikin. ⋯ The impact of backboard orientation was also found to be important with a longitudinal orientation producing an increase in compression stiffness of as much as 60.3% relative to a latitudinal orientation. Backboard configuration should be considered by clinicians when trying to achieve optimal CC performance during CPR in hospital settings.