Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
-
Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Support vector machine classification of multi-channel EEG traces: a new tool to analyze the brain response to morphine treatment.
The analgesic effect of morphine is highly individual, calling for objective methods to predict the subjective pain relief. Such methods might be based on alteration of brain response caused by morphine during painful stimuli. The study included 11 healthy volunteers subjectively quantifying perception of painful electrical stimulations in the esophagus. ⋯ The most discriminative feature was a decrease in the delta band (0.5 - 4 Hz) after morphine for volunteers with analgesic effect. Volunteers with no effect of morphine showed an increase in the delta band after drug administration. As only a proportion of patients benefit from opioid treatment, the new approach may help to identify non-responders and guide individualized tailored analgesic therapy.
-
Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Artifact reduction based on Empirical Mode Decomposition (EMD) in photoplethysmography for pulse rate detection.
The pulstile components of photoplethysmography (PPG) contain valuable information about a subject's cardiovascular and metabolic systems. Pulse rate is one of the most significant vital signs that can be extracted from PPG signals. However, patient movement, especially movement at the measurement sites, such as fingers, can disturb the PPG's light path significantly, resulting in corrupted measurements. ⋯ The proposed method was used to recover PPG signals recorded in an experiment, where motion artifacts were intentionally introduced by finger bending. By using our method, the signal-to-noise ratio was increased from 0.078 dB of the contaminated signals to 0.318 dB, and the true detection rate of heartbeats was improved from 59.2% to 96.6%. The results demonstrated that the EMD combined with Hilbert transform has great potential in reducing motion artifacts in PPG signals and can improve the accuracy of heartbeat detection.
-
Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Comparative StudyTime-varying spectral analysis for comparison of HRV and PPG variability during tilt table test.
In this work we assessed the possibility of using the pulse rate variability (PRV) extracted from photoplethysmography signal as an alternative measurement of the HRV signal in non-stationary conditions. The study is based on the analysis of the changes observed during tilt table test in the heart rate modulation of 17 young subjects. Time-varying spectral properties of both signals were compared by time-frequency (TF) and TF coherence analysis. ⋯ Time-frequency analysis revealed that: the TF spectra of both signals were highly correlated (0.99 ± 0.01); the difference between the instantaneous power, in LF and HF bands, obtained from HRV and PRV was small (, 10(-3) s(-2)) and their temporal patterns were highly correlated (0.98 ± 0.04 and 0.95 ± 0.06 in LF and HF bands respectively); TF coherence in LF and HF bands was high (0.97 ± 0.04 and 0.89 ± 0.08, respectively). Finally, the instantaneous power in LF band was observed to significantly increase during head-up tilt by both HRV and PRV analysis. These results suggest that, although some small differences in the time-varying spectral indices extracted from HRV and PRV exist, mainly in the HF band associated with respiration, PRV could be used as an acceptable surrogate of HRV during non-stationary conditions, at least during tilt table test.
-
Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Preliminary assessment of abdominal organ perfusion utilizing a fiber optic photoplethysmographic sensor.
In an attempt to overcome the limitations of current techniques for monitoring abdominal organ perfusion, a prototype reflectance fiber optic photoplethysmographic (PPG) sensor and processing system was evaluated on seventeen anaesthetized patients undergoing laparotomy. Good quality PPG signals were obtained from the large bowel, small bowel, liver and stomach. ⋯ Mean estimated blood oxygen saturation (SpO(2)) values from all abdominal sites showed good agreement with those obtained from the finger using both the finger fiber optic sensor and a commercial finger pulse oximeter. Furthermore, a Bland and Altman between-method-differences analysis on the estimated SpO(2) data suggests that a fiber optic abdominal sensor may be a suitable method for the evaluation of abdominal organ perfusion.
-
Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Clinical TrialAssessment of the depth of anesthesia based on symbolic dynamics of the EEG.
Methodologies based on symbolic dynamics have successfully demonstrated to reflect the nonlinear behavior of biological signals. In the present study, symbolic dynamics was applied to the electroencephalogram (EEG) in order to describe the level of depth of anesthesia. ⋯ Words of three symbols were built from this symbolic series. The results obtained from the EEGs of 36 patients undergoing anesthesia showed that the probabilities of the word types were able to reflect the depth of anesthesia in a similar way to the auditory evoked potential index AAI, a commercial index.