Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Merging PK/PD information in a minimally parameterized model of the neuromuscular blockade.
A recursive system identification algorithm that merges PK/PD information in a minimally parameterized Wiener model for the NMB level is presented. The results show that the coupling between one parameter from the linear block and one from the static nonlinearity is advantageous, when evaluated on a database of 60 real collected NMB cases.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Steering deep brain stimulation fields using a high resolution electrode array.
Deep brain stimulation (DBS) therapy relies on electrical stimulation of neuronal elements in small brain targets. However, the lack of fine spatial control over field distributions in current systems implies that stimulation easily spreads into adjacent structures that may induce adverse side-effects. ⋯ Our computational analysis demonstrates that the DBS-array is capable of accurately displacing activation volumes with sub-millimeter precision. Our findings demonstrate that future systems for DBS therapy may provide for more accurate target coverage than currently available systems achieve.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Effect of ECG quality measures on piecewise-linear trend detection for telehealth decision support systems.
Fledgling clinical decision support systems (DSSs) are being designed on the false assumption that consistent, good-quality signals are created in the unsupervised telehealth environment, but it has in fact been shown that signal quality is often very poor. Hence, it is important to investigate the detrimental impact of failing to recognize erroneous clinical parameter values. ⋯ The application of the same artifact detection also results in a significant improvement in trend fitting, when compared to a fitting of the reference HR values, by reducing the mean RMSE value of the error in the trend fit from 2.14 BPM to 0.78 BPM and standard error from 0.49 BPM to 0.10 BPM. As trend detection will be a component of future telehealth decision support systems, signal quality measures for unsupervised measurements are of paramount importance.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Intraoperative multichannel audio-visual information recording and automatic surgical phase and incident detection.
Identification, analysis, and treatment of potential risk in surgical workflow are the key to decrease medical errors in operating room. For the automatic analysis of recorded surgical information, this study reports multichannel audio visual recording system, and its review and analysis system. ⋯ Conversation among surgical staff is quantified using fast Fourier transformation and frequency filter without speech recognition. The results suggested the progression phase of surgical procedure.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Towards improved sedation control in critically ill patients.
Patients in intensive care units are often prescribed a combination of sedative and analgesic to manage anxiety and pain relief. Proper sedation management is crucial to patient recovery but few intensive care units routinely employ strategies that tailor drug delivery to ongoing patient needs. The Infuse-Rite has been developed to automate a protocol that eliminates the possibility of excessive sedation. Changing clinical demands have provided the impetus for ongoing enhancements to improve the sedation control of patients in intensive care.