Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Theoretical simulation of the dual-heat-flux method in deep body temperature measurements.
Deep body temperature reveals individual physiological states, and is important in patient monitoring and chronobiological studies. An innovative dual-heat-flux method has been shown experimentally to be competitive with the conventional zero-heat-flow method in its performance, in terms of measurement accuracy and step response to changes in the deep temperature. ⋯ The corresponding depth of the estimated temperature in the skin and subcutaneous tissue layer is consistent when using the dual-heat-flux probe. Insights in improving the performance of the dual-heat-flux method were discussed for further studies of dual-heat-flux probes, taking into account structural and geometric considerations.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Robust closed-loop control of propofol administration using WAVCNS index as the controlled variable.
This paper presents a robust closed-loop strategy for control of depth of hypnosis. The proposed method regulates the electroencephalogram (EEG)-derived WAVCNS index as a hypnosis measure by manipulating intravenous propofol administration. ⋯ This closed-loop control was evaluated using simulated surgical procedures in 44 patient models whose PK and PD were identified from real clinical data. The controller can deliver consistent and acceptable closed-loop induction and maintenance phase responses for patients with wide-ranging PK and PD differences.
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In recent years there has been a rapid growth in patient monitoring and medical data analysis using a number of computer-aided systems based on expert systems, fuzzy logic and many other intelligent techniques. Fuzzy logic-based expert systems have shown potential to improve clinician performance by imitating human thought processes in complex circumstances and accurately executing repetitive tasks to which humans are ill-suited. ⋯ The performance of the system was validated through a series of off-line tests. When detecting hypovolaemia a substantial level of agreement was observed between FLMS and the human expert (the anaesthetist) during surgical procedures.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Estimated venous return surface and cardiac output curve precisely predicts new hemodynamics after volume change.
In our extended Guyton's model, the ability of heart to pump blood is characterized by a cardiac output curve and the ability of vasculature to pool blood by a venous return surface. These intersect in a three-dimensional coordinate system at the operating right atrial pressure, left atrial pressure, and cardiac output. ⋯ Using the average values for two logarithmic function parameters, and for two slopes of a surface, we were able to estimate cardiac output curve and venous return surface. The estimated curve and surface predicted new hemodynamics after volume change precisely.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
A closed-loop brain computer interface for real-time seizure detection and control.
The worldwide prevalence of epilepsy is approximately 1%, and 25% of epilepsy patients cannot be treated sufficiently by available therapies. Brain stimulation with closed-loop seizure control has recently been proposed as an innovative and effective alternative. ⋯ A wireless communication feature also provided flexibility for subjects freeing from the hassle of wires. Experimental data from freely moving rats supported the functional possibility of a real-time closed-loop seizure controller.