The Journal of the Association of Physicians of India
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J Assoc Physicians India · Dec 2013
Prevention of thromboembolic complication in atrial fibrillation by using anticoagulants.
Atrial fibrillation is the most common type of arrhythmia in adults. Atrial fibrillation occurs as paroxysms or may become established as permanent condition. Patients with atrial fibrillation are at increased risk for thromboembolic disease. ⋯ Warfarin significantly reduces incidence of stroke in AF patients.
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J Assoc Physicians India · Dec 2013
Case ReportsRecurrent angio-oedema--three cases of C1 inhibitor deficiency.
C1 Inhibitor deficiency is a rare disorder, characterised by recurrent angio-oedema of skin, upper respiratory and gastrointestinal tracts. It can be a mimicker of acute abdomen or anaphylaxis to drug or food and lead on to unnecessary overtreatment. Three case reports of such patients with history of recurrent abdominal pain and angio-oedema due to C1 Inhibitor deficiency is reported here.
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J Assoc Physicians India · Nov 2013
Case ReportsHaemophagocytic lymphohistiocytosis (HLH): case series in tertiary referral hospital over three years.
Haemophagocytic lymphohistiocytosis (HLH) is a rare but potentially fatal disease of normal but overactive histiocytes and lymphocytes that commonly appears in infancy, although it has been seen in all age groups. We are reporting a series of 5 cases of HLH in young adult and paediatric patients identified over three years.
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J Assoc Physicians India · Oct 2013
Randomized Controlled Trial Multicenter StudyRandomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated diarrhoea.
To evaluate the effectiveness, safety and tolerability of a probiotic formulation containing Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 in the prevention of antibiotic associated diarrhoea (AAD). ⋯ This randomised controlled trial shows that prophylactic administration of the probiotic formulation containing Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12, did not effectively lower the incidence of AAD in adults. However, compared to placebo the duration of diarrhoea in the probiotic group was significantly reduced. Its tolerability and safety profile were good.
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Lemierre's syndrome is an acute oropharyngeal infection with secondary septic thrombophlebitis of the internal jugular vein and frequent metastatic infections. Despite its rarity, it is important to have a high degree of clinical suspicion to recognise it early. A history of sore throat followed by metastatic infections and abscesses should alert the clinician to the possibility of this unusual infection. We present a case of Lemierre's syndrome presenting with meningitis in a previously healthy young adult along with a review of the pathophysiology of necrobacillosis and its diagnosis, diagnostic difficulty and treatment.