The Journal of the Association of Physicians of India
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J Assoc Physicians India · May 2012
Study of clinical profile in patients with H1N1 influenza in Surat district, June 2009-March 2010.
During spring of 2009, pandemic of Influenza A (H1N1) virus emerged and spread globally. We describe the clinical profile of patients who were found H1N1 Positive in Surat district from 27th June 2009 to march 2010. ⋯ During evaluation period, 2009 H1N1 influenza caused severe illness requiring hospitalization, including pneumonia and respiratory distress and co-morbid condition. Maximum patients were between age group of 14-50 year. Fever and cough were most common presenting symptoms. Nearly 36.36% patients had one or more underlying medical conditions. Mechanical ventilatory support had role in reduction in mortality. Patients seemed to be benefited from antiviral therapy if started within 72 hour of onset of symptom. There were no significant side effects of Oseltamivir observed in this study. Development of ARDS, requirement of Mechanical ventilation and having co-morbid condition were poor prognostic factors. We observed two peaks of H1N1 during this period second peak was less severe than first one. It may be due to development of immunity, Disease awareness, early diagnosis and treatment and health education.
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J Assoc Physicians India · Apr 2012
ReviewAllergic bronchopulmonary aspergillosis--a clinical review.
Allergic Bronchopulmonary Aspergillosis (ABPA) was first described by Hinson and colleagues in 1952. ABPA is a hypersensitivity disorder induced by a fungus Aspergillus and affects non-immunocompromised patients. The diagnosis is based on the presence of a combination of clinical, biological and radiological criteria. The treatment is based on oral corticosteroids for 6-8 weeks at acute phase or exacerbation and Itraconazole is now recommended and validated at a dose of 200 mg/day for 16 weeks.
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J Assoc Physicians India · Mar 2012
Persistent high prevalence of cardiovascular risk factors in the urban middle class in India: Jaipur Heart Watch-5.
Urban subjects have high burden of cardiovascular risk factors, therefore, to evaluate risk factors in middle socioeconomic subjects and to study secular trends we performed an epidemiological study. ⋯ There is a high prevalence of multiple cardiovascular risk factors in Indian middle class individuals. Secular trends demonstrate a persistent high prevalence and increasing non-HDL cholesterol and triglycerides over 8-year period.