The Journal of the Association of Physicians of India
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This study was undertaken to determine incidence, clinical features, microbiological flora and prognosis of patients with nosocomial pneumonia (NP) in medical intensive care unit (ICU). Also to study impact of comorbid illnesses, intubation and mechanical ventilation on outcome. ⋯ Nosocomial pneumonias constitute important problem in medical ICU and are associated with high mortality. Patients with advanced age, co-morbid illness, ARDS and end organ failure are at high risk for mortality. However with intensive supportive care and appropriate antibiotics many such lives can be saved.
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J Assoc Physicians India · Oct 2000
ReviewStevens-Johnson syndrome and toxic epidermal necrolysis-challenges of recognition and management.
Skin adverse drug reactions (ADRs) generally present as transient erythematous macular/papular rashes. However these can many a times be the initial presentation of serious muco-cutaneous ADRs such as Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN). The incidence of SJS varies from 1.2 to 6 per million patient-years and that of TEN to be 0.4 to 1.2 per million patient-years. ⋯ The use of systemic corticosteroids has been controversial. Early diagnoses can prevent/reduce the morbidity of such serious ADRs. This article provides a brief review of the clinical presentation and management of SJS and TEN.
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A 34 years non diabetic lady with chronic myeloid leukaemia (CML) was treated with hydroxyurea and interferon. She developed leg ulcers. ⋯ Both were treated with local wound care and antibiotics. First time dose of hydroxyurea was reduced and second time drug was discontinued.
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J Assoc Physicians India · Sep 2000
Comment Letter Case ReportsParacetamol (acetaminophen) poisoning: report of two cases.
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J Assoc Physicians India · Aug 2000
Letter Case ReportsAluminium phosphide (ALP) is a widely used fumigant posticide.