Anales españoles de pediatría
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Randomized Controlled Trial Clinical Trial
[Efficacy of early administration of nebulized ipratropium bromide in children with asthmatic crisis].
To determine the efficacy of adding ipratropium bromide to nebulized salbutamol in the treatment of children with moderate-to-severe acute asthma attacks. ⋯ Coadministration of ipratropium bromide and repeat doses of nebulized salbutamol produced a small beneficial clinical effect compared with administration of nebulized salbutamol alone. This beneficial effect was related to a decrease in the hospitalization rate, particularly in patients with severe asthma attacks.