Anales españoles de pediatría
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Sixty-four preterm infants (birth weight 1,393 +/- 483 g g and gestational age 30.1 +/- 2.7 weeks) developed a symptomatic ductus arteriosus, and were treated with intravenous indomethacin. Mechanical ventilation was needed by all of them, and 98% had IRDS. Pharmacologic ductus closure rate was 87%. ⋯ Closure rate was higher in this group of patients treated with intravenous indomethacin, than in a previous group of a similar birth weight and gestational age, who received the drug by oral route (87% versus 64%). Incidence of necrotizing enterocolitis was found to be similar in both groups. Follow-up data showed that four infants (8.5%) had severe neurological sequelae, and another three cases (6.4%) developed severe respiratory problems.
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The smoking habit within the family produces various harmful effects on child health when the child is considered as a passive smoker. In this paper we have reviewed the most recent studies which analyze the influence of parental smoking on the incidence of respiratory diseases, alteration in the pulmonary function and presence of other symptoms, during the first years of life. A number of recommendations have been extracted to prevent these problems during childhood.