Therapeutische Umschau. Revue thérapeutique
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Substance use disorders (SUD) include substance abuse and dependence as well as acute intoxication, withdrawal, and various psychiatric disorders. In the course of the SUD, severe comorbid disorders and somatic consequences can occur. The treatment of withdrawal symptoms focuses on the relief of immediate symptoms and the prevention of complications. ⋯ There is consistent evidence for methylphenidate in treating cocaine dependence co-occurring with attention-deficit/hyperactivity disorder. For opioid dependence, methadone or buphrenorphine treatment is the pharmacotherapy of first choice. Nicotine replacement therapy, Bupropion and Vareniclin are efficacious in smoking cessation.